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. 2009 Mar 24;8:50. doi: 10.1186/1475-2875-8-50

Table 2.

TLR2, 4, 9, and MAL genotypes in various populations

PNG Kenya North America
PolymorphismI genotype lowlands lowlands highlands African Caucasian Asian
TLR2 Δ22 WW 253(76) 41(49) 33(48) 58(62) 64(76) 49(58)
WDII 73(22) 36(43) 27(39) 30(32) 18(21) 27(32)
DD 7(2) 7(8) 9(13) 5(5) 2(2) 8(10)
TLR4 Asp299Gly Asp/Asp 906(100)IV 78(86) 66(89) 65(74) 67(83) 76(92)
Asp/Gly 0 13(14) 8(11) 23(26) 14(17) 7(8)
TLR4 Thr399Ile Thr/Thr 906(100)IV 64(97) 69(99) 84(94) 64(81) 77(93)
Thr/Ile 0 2(3) 1(1) 5(6) 15(19) 6(7)
TLR9 -1486 TT 137(41) 47(54) 41(54) 37(42) 36(44) 34(41)
CT 146(44) 33(38) 32(42) 43(48) 35(43) 38(46)
CC 51(15) 7(8) 3(4) 9(10) 10(12) 11(13)
TLR9 -1237 TT 334(100) 39(45) 29(38) 36(40) 61(75) 74(89)
CT 0 35(40) 39(51) 46(52) 19(23) 7(8)III
CC 0 13(15) 8(11) 7(8) 1(1) 2(2)
TLR9 1174 GG 53(16) 29(32) 17(22) 35(43) 22(27) 14(17)
GA 147(44) 47(53) 47(60) 38(46) 33(41) 40(48)
AA 136(41) 12(14) 14(18) 9(11) 26(32) 29(35)
MAL 180 Ser/Ser 254(73) 89(100) 75(95) 82(91) 53(68) 73(88)
Ser/Leu 81(23) 0 4(5) 6(7)III 25(32) 10(12)
Leu/Leu 11(3) 0 0 2(2) 0 0

Ino.(%)

IID is deletion allele, W is wild type/insertion allele

IIIp < .05, Hardy-Weinberg test of equilibrium, deficit of heterozygosity

IVgenotyped previously [50]