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. 2009 Mar 24;8:50. doi: 10.1186/1475-2875-8-50

Table 3.

TLR2, TLR4, and TLR9 haplotypes in various populations

PNG Kenya North America
Gene Haplotype lowlands lowlands highlands African Caucasian Asian
TLR2I
DL 0.029 0.000 0.000 0.000 0.000 0.086
DM 0.011 0.258 0.239 0.164 0.099 0.105
DS 0.093 0.041 0.092 0.051 0.033 0.063
WL 0.355 0.110 0.100 0.161 0.388 0.300
WM 0.509 0.559 0.515 0.572 0.480 0.293
WS 0.003 0.033 0.054 0.052 0.000 0.154
TLR4II
Asp-Thr 1IV 0.924 0.943 0.869 0.905 0.952
Gly-Ile 0 0.015 0.007 0.028 0.089 0.030
Gly-Thr 0 0.061 0.050 0.102 0.000 0.012
Asp-Ile 0 0.000 0.000 0.000 0.006 0.006
TLR9III
C C A 0.000 0.006 0.007 0.000 0.000 0.000
C C G 0.000 0.075 0.099 0.092 0.000 0.011
C T A 0.003 0.000 0.011 0.018 0.000 0.007
C T G 0.368 0.205 0.136 0.244 0.353 0.343
T C G 0.000 0.266 0.254 0.256 0.115 0.055
T T A 0.625 0.396 0.455 0.324 0.526 0.584
T T G 0.005 0.051 0.037 0.066 0.006 0.000

IΔ22-GTn haplotypes

D is deletion allele, W is wild type

S < 16 repeats, M 16–23 repeats, L > 23 repeats.

IIFirst amino acid is 299, second amino acid is 399

IIIFirst nucleotide is -1486, second is -1237, and third is 1174.

IVGenotyped previously [50]