Table 3.
TLR2, TLR4, and TLR9 haplotypes in various populations
| PNG | Kenya | North America | |||||
| Gene | Haplotype | lowlands | lowlands | highlands | African | Caucasian | Asian |
| TLR2I | |||||||
| DL | 0.029 | 0.000 | 0.000 | 0.000 | 0.000 | 0.086 | |
| DM | 0.011 | 0.258 | 0.239 | 0.164 | 0.099 | 0.105 | |
| DS | 0.093 | 0.041 | 0.092 | 0.051 | 0.033 | 0.063 | |
| WL | 0.355 | 0.110 | 0.100 | 0.161 | 0.388 | 0.300 | |
| WM | 0.509 | 0.559 | 0.515 | 0.572 | 0.480 | 0.293 | |
| WS | 0.003 | 0.033 | 0.054 | 0.052 | 0.000 | 0.154 | |
| TLR4II | |||||||
| Asp-Thr | 1IV | 0.924 | 0.943 | 0.869 | 0.905 | 0.952 | |
| Gly-Ile | 0 | 0.015 | 0.007 | 0.028 | 0.089 | 0.030 | |
| Gly-Thr | 0 | 0.061 | 0.050 | 0.102 | 0.000 | 0.012 | |
| Asp-Ile | 0 | 0.000 | 0.000 | 0.000 | 0.006 | 0.006 | |
| TLR9III | |||||||
| C C A | 0.000 | 0.006 | 0.007 | 0.000 | 0.000 | 0.000 | |
| C C G | 0.000 | 0.075 | 0.099 | 0.092 | 0.000 | 0.011 | |
| C T A | 0.003 | 0.000 | 0.011 | 0.018 | 0.000 | 0.007 | |
| C T G | 0.368 | 0.205 | 0.136 | 0.244 | 0.353 | 0.343 | |
| T C G | 0.000 | 0.266 | 0.254 | 0.256 | 0.115 | 0.055 | |
| T T A | 0.625 | 0.396 | 0.455 | 0.324 | 0.526 | 0.584 | |
| T T G | 0.005 | 0.051 | 0.037 | 0.066 | 0.006 | 0.000 | |
IΔ22-GTn haplotypes
D is deletion allele, W is wild type
S < 16 repeats, M 16–23 repeats, L > 23 repeats.
IIFirst amino acid is 299, second amino acid is 399
IIIFirst nucleotide is -1486, second is -1237, and third is 1174.
IVGenotyped previously [50]