Table 2.

Monocyte recruitment in CXCR2 +/+, +/−, and −/− mice after nitrogen mustard wounding

	CXCR2 Genotype
Time post-wounding (d)	+/+	+/−	−/−
4	38.33 ± 0.88	47.00 ± 2.00	39.67 ± 1.20
7	22.33 ± 0.88	40.00 ± 0.57	38.00 ± 1.15*
10	19.66 ± 0.66	17.33 ± 0.57	25.33 ± 1.45*

Monocyte infiltration to the wound bed on days 4, 7, and 10 after chemical wounding of the skin with NM. Total numbers of monocyte in CXCR2 wild type, CXCR2 heterozygous, and CXCR2 knockout mice were manually determined and counted along the wounded areas at 100×. Data are expressed as the mean ± SEM. Statistical significance of the comparison between CXCR2 wild type, CXCR2 knockout, and CXCR2 heterozygous mice, was based upon the Student’s two-tailed t-test. The level of statistical significance of the comparison between wild type and CXCR2 (−/−) mice is indicated by the * denote p values < 0.05, showing statistical difference between these two genotypes at postwound day 7 and 10.