Bivariate model adapted from reference 38. VE, vigorous exercise; A1 and A2, additive genetic effects for twins 1 and 2 within a twin pair, respectively; C1 and C2, shared environmental effects for twins 1 and 2 within a twin pair, respectively; Mi, age moderator values for the ith individual within each twin pair; ra, additive genetic correlation; rc, shared environmental correlation; re, nonshared environmental correlation.