TABLE 2.
Relative risks and 95% CIs for sugar-sweetened beverage consumption and risk of coronary heart disease by consumption level (n = 88,520)
| Consumption level |
||||||
| <1/mo | 1–4/mo | 2–6/wk | 1 to <2/d | ≥2/d | P for trend | |
| Median intake (servings/d) | 0 | 0.1 | 0.4 | 1.2 | 2.6 | |
| No. of cases | 883 | 723 | 1198 | 218 | 83 | |
| Person-years | 574,814 | 494,831 | 745,176 | 134,933 | 52,455 | |
| Age-adjusted | 1 | 0.94 (0.85, 1.03) | 1.08 (0.99, 1.18) | 1.51 (1.30, 1.75) | 1.93 (1.54, 2.43) | <0.001 |
| Multivariate-adjusted1 | 1 | 0.97 (0.88, 1.07) | 1.06 (0.97, 1.16) | 1.27 (1.09, 1.47) | 1.39 (1.11, 1.75) | <0.001 |
| Multivariate-adjusted + diet2 | 1 | 0.96 (0.87, 1.06) | 1.04 (0.95, 1.14) | 1.23 (1.06, 1.43) | 1.35 (1.07, 1.69) | <0.001 |
1
Adjusted for age (continuous), smoking [never, past, or current cigarette use (1–14/d, 15–24/d, ≥25/d, or missing)], alcohol intake (0, <5, 5–15, or >15 g/d), family history (yes or no), physical activity (quintiles), aspirin use (<1, 1–2, 3–6, 7–14, or ≥15/wk), menopausal status and postmenopausal hormone use (premenopausal, never, past, or current hormone use), and history of hypertension and high blood cholesterol. Relative risks were computed from a Cox proportional hazard model.
2
Additionally adjusted for the Alternate Healthy Eating Index (quintiles).