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Distributions of GALK1 activities according to the genotypes at c.-22 of the GALK1 gene are plotted according to patient age. The GALK1 values for the genotype C/C, T/C, and T/T at nucleotide -22 are indicated as ▲, ●, and □, respectively. The GALK1 activities in individuals having at least one C allele (T/C or C/C genotype) were significantly higher than those in individuals with the T/T genotype (p < 0.001 by Mann-Whitney U test).
