Table 1.
Selected characteristics of SCC cases by age at diagnosis*
| 22–35 years old n=165 |
36–53 years old n=168 |
|||
|---|---|---|---|---|
| Characteristic | Frequency† | % | Frequency | % |
| Age (years) | ||||
| Mean (standard deviation) | 31.0 (3.2) | 41.1 (4.0) | ||
| Median | 32 | 40 | ||
| Birth year | ||||
| 1951–1959 | 73 | 44 | 120 | 71 |
| 1960–1967 | 92 | 56 | 48 | 29 |
| Race | ||||
| White | 152 | 92 | 143 | 85 |
| Non-White | 13 | 8 | 25 | 15 |
| Education | ||||
| High school or less | 74 | 45 | 62 | 37 |
| More than high school | 91 | 55 | 106 | 63 |
| Income | ||||
| Less than $30,000 per year | 93 | 57 | 64 | 39 |
| $30,000 per year or more | 71 | 43 | 100 | 61 |
| Unknown | 1 | 4 | ||
| Marital status | ||||
| Never married | 27 | 16 | 21 | 13 |
| Ever married ‡ | 138 | 84 | 147 | 88 |
| Cigarette smoking | ||||
| Never | 49 | 30 | 74 | 44 |
| Former | 48 | 29 | 33 | 20 |
| Current | 68 | 41 | 61 | 36 |
| Age at menses (years) | ||||
| Less than 12 | 32 | 19 | 34 | 20 |
| 12 to 13 | 80 | 48 | 94 | 56 |
| 14 or older | 53 | 32 | 40 | 24 |
| Combined OC use | ||||
| Never to <6 months | 29 | 18 | 52 | 31 |
| 6 months to < 5 years | 57 | 35 | 59 | 35 |
| 5 or more years | 79 | 48 | 57 | 34 |
| Number of full term pregnancies | ||||
| 0 | 46 | 28 | 30 | 18 |
| 1 | 41 | 25 | 30 | 18 |
| 2 or more | 78 | 47 | 108 | 64 |
| Full term pregnancy rate | ||||
| None | 18 | 11 | 15 | 9 |
| < 1 per 10 years | 29 | 18 | 57 | 34 |
| 1 per 10 to <2 per 10 years | 55 | 34 | 61 | 37 |
| 2 per 10 years or greater | 62 | 38 | 34 | 20 |
| Pap frequency in most recent decade | ||||
| None | 7 | 4 | 2 | 1 |
| 1 to 5 per decade | 67 | 41 | 102 | 63 |
| 6 to 8 per decade | 10 | 6 | 15 | 9 |
| 1 per year | 61 | 37 | 34 | 21 |
| Greater than 1 per year | 19 | 12 | 10 | 6 |
| Unknown | 1 | 5 | ||
| Lifetime number of sex partners | ||||
| 1 | 5 | 3 | 11 | 7 |
| 2 to 4 | 46 | 28 | 52 | 31 |
| 5 to 14 | 74 | 45 | 69 | 41 |
| 15 or more | 40 | 24 | 35 | 21 |
| Unknown | 0 | 1 | ||
| Chlamydia trachomatis serology§ | ||||
| Negative | 45 | 52 | 26 | 58 |
| Positive | 41 | 48 | 19 | 42 |
| Test not performed or unknown | 79 | 123 | ||
| HSV-2 serology § | ||||
| Negative | 79 | 56 | 34 | 47 |
| Positive | 61 | 44 | 39 | 53 |
| Test not performed or unknown | 25 | 95 | ||
| FIGO Stage | ||||
| Stage 1 | 151 | 92 | 131 | 81 |
| Stage 2–4 | 13 | 8 | 30 | 19 |
| Unknown | 1 | 7 | ||
| HPV DNA results | ||||
| HPV negative | 14 | 11 | 9 | 9 |
| HPV-16 positive | 88 | 71 | 60 | 62 |
| HPV-18 positive | 8 | 6 | 10 | 10 |
| HPV-16 and -18 positive | 6 | 5 | 9 | 9 |
| HPV positive for other types** | 8 | 6 | 9 | 9 |
| HPV positive, type unknown | 3 | 0 | ||
| Insufficient sample | 8 | 3 | ||
| Test not performed or unknown | 30 | 68 | ||
| HPV 16/18 serology | ||||
| HPV-16 and -18 negative | 80 | 56 | 30 | 42 |
| Only HPV-16 positive | 29 | 20 | 14 | 19 |
| Only HPV-18 positive | 13 | 9 | 16 | 22 |
| HPV-16 and -18 positive | 20 | 14 | 12 | 17 |
| Test not performed or unknown | 23 | 96 | ||
*
SCC= squamous cell cervical cancer, HSV-2=Herpes simplex virus type 2, FIGO=International Federation of Gynecology, and Obstetrics (FIGO), HPV=Human papillomavirus
†
Unless otherwise indicated
‡
Includes currently or formerly married or lived with a partner for greater than 6 months
§
Chlamydia trachomatis, HSV-2, HPV-16 and HPV-18 serology only available on cases enrolled prior to 1999, which excludes 94 cases (88 diagnosed at 36–53 years of age and 8 diagnosed at 22–36 years of age)
**
Includes HPV types 6, 31, 33, 45, 53, 58, and/or 73