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Effects of sec-23 RNAi on larvae. (A) An untreated wild-type L4 larva. (B–F) Larvae subjected to sec-23 RNAi by the bacterial feeding method. (B) An animal of age similar to that in A, showing a lack of growth. (C) An animal that ruptured upon handling, demonstrating a weak cuticle. (D) An accumulation of undigested bacteria (arrows) in the intestine. (E) A molting defect; the head of an animal is stuck inside an old cuticle. (F) Bloated seam cells. Bars, 0.1 mm.
