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. Author manuscript; available in PMC: 2010 Mar 1.
Published in final edited form as: Pharmacogenet Genomics. 2009 Mar;19(3):239–243. doi: 10.1097/FPC.0b013e328323f66c

Table 4.

UGT1A1 promoter haplotypes and endometrial cancer risk in WHS and NHS

UGT1A1 haplotype −3279 G/T −3156 G/A TA repeat number Cases (%) Controls (%) OR (95% CI)1 Adjusted OR (95% CI)2
I T G 6 56.5 54.8 1.00 1.00
II G A 7 29.0 29.5 0.97 (0.82, 1.13) 0.95 (0.80, 1.13)
III G G 6 10.5 11.4 0.83 (0.65, 1.07) 0.91 (0.69, 1.20)
IV G G 7 3.1 3.5 0.86 (0.57, 1.32) 0.91 (0.57, 1.44)
1

Conditional logistic regression model conditioned on the strata defined by the matching variables: age, menopausal status and postmenopausal hormone use at blood collection, date of blood draw, time of blood draw, and fasting status at blood draw.

2

Conditional logistic regression model conditioned on the strata defined by the matching variables and body mass index at diagnosis, age at menarche, age at menopause, menopausal status and postmenopausal hormone use at diagnosis, first-degree family history of colorectal cancer, parity, age at first birth, and smoking status.