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Effect of MNF, H89, and PP2 on the action of TCDD after 72 h treatment. MCF10A cells were preincubated with 10 μm MNF, 2 μm H89, or 2 μm PP2, respectively, for 30 min and then treated with 10 nm TCDD for 72 h. The mRNA induction levels of selected genes were measured. The results are expressed as fold of induction after TCDD treatment, and the statistically significant differences between the TCDD-only group and other groups are indicated by * (P < 0.05) or ** (P < 0.01).
