TABLE 1.
Data collection and refinement statistics
| EGF-AB | Wild-type, pH 7.4 | H306Y, pH 7.4 |
|---|---|---|
| Space group | P4(1)2(1)2 | P4(1)2(1)2 |
| a, b | 116.047 Å | 115.661 Å |
| c | 133.629 Å | 133.401 Å |
| Resolution (Å) (final shell) | 40.0 to 2.70 | 40.0 to 2.70 |
| (2.77 to 2.70) | (2.77 to 2.70) | |
| Reflections | ||
| Total | 110,489 | 117,756 |
| Unique | 24,921 | 25,367 |
| Completeness | 96.6% (81.9%) | 99.3% (92.8%) |
| Rsym | 8.4% | 8.1% |
| Rcryst | 22.6% (34.7%) | 23.4% (33.2%) |
| Rfree | 26.1% (46.5%) | 27.8% (41.2%) |
| Root mean square deviation | ||
| Bond length | 0.006 Å | 0.006 Å |
| Bond angle | 0.973° | 0.971° |