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Up-regulation of genes involved in nonfermentable carbon source metabolism is suppressed in Δisc1. Logarithmically growing cells were inoculated to YPD medium and incubated for the indicated times. A and B, expression of ADH2 (A) and CTA1 (B) quantitated by real time RT-PCR in WT and Δisc1. The results are means of relative expression of at least three experiments with error bars showing S.E.
