FIGURE 8.

Retrograde response is not apparently up-regulated in pre-diauxic phase of Δisc1. The plot of fold change in expression of the genes in the Δisc1 strain versus the parental strain when grown in YPD was determined and graphed versus induction in petite cells (which exhibit the retrograde response) (44). Regression analysis was used to establish a trend line (dashed line), which indicated little to no correlation between retrograde gene induction and gene induction in the Δisc1 strain (R² = 0.0089). Fold change is shown as the mean of two independent experiments ± S.E.