FIGURE 3.
Cathepsin-D processing and activity in Mreg-/- mouse retinas. A, Cat-D activity in retinal lysates from Mreg-/- mice (white bar) and Mreg+/+ C57BL/J6 retinas (solid bar). Results are an average of three preparations each consisting of three retinas with assays performed in triplicate (n = 9). Values are average ± standard deviation (error bars). B, representative immunoblot (IB) of cleared everted eyecup lysates from Mreg-/- and Mreg+/+ adult mice. Lysates were prepared from everted eyecups isolated 3 h after lights on.