Table II.
Raw and age-adjusted mean telomere length
Sample group | N | Mean age (years) | Mean telomere length |
P-valuea,b | |
---|---|---|---|---|---|
Raw data (±SD) (kb) | Age-adjusted (kb) | ||||
Control group 1 | 108 | 36.3 | 8.98 ± 1.15 | 8.92 | |
Control group 2 | 46 | 41.5 | 8.99 ± 1.03 | 9.11 | 0.36 |
POF patients | 34 | 35.4 | 9.61 ± 1.38 | 9.58 | 0.01, 0.32 |
RM | 95 | 35.8 | 8.47 ± 0.92 | 8.46 | 0.0004, 0.02 |
Single trisomy | 32 | 36.3 | 8.80 ± 0.78 | 8.80 | 0.39, 0.26 |
Multiple trisomy | 17 | 39.3 | 8.42 ± 0.69 | 8.52 | 0.11, 0.06 |
aP-values in comparison with Control groups 1 and 2, respectively.
bAnalysis of covariance (k = 2 in comparison with Control group 1 or 2) was used to adjust raw telomere length data by age in comparisons between groups.