Table 1.

Target sites of M. tuberculosis glutamine synthetase-specific antisense PS-ODNs

	Antisense PS-ODN 4–9	Antisense PS-ODN 269–275	Antisense PS-ODN 275-282
glnA1 region 5′ > 3′	rowAAGACGCCCGACGACGTC	cellGGCGACAACGGGTCCGGCATG	cellATGCACTGTCATCAGTCGCTGTGG
glnA1 mRNA 5′ > 3′	rowAAGACGCCCGACGACGUC	rwoGGCGACAACGGGUCCGGCAUG	cellAUGCACUGUCAUCAGUCGCUGUGG
PS-ODN sequence 5′ > 3′	rowGACGTCGTCGGGCGTCTT	cellCATGCCGGACCCGTTGTCGCC	cellCCACAGCGACTGATGACAGTGCAT
PS-ODN length	18 nt	21 nt	24 nt
PS-ODN GC content	66.7%	71.4%	54.2%
Propensity of PS-ODN to remain linear	Weak	Strong	Moderate

glnA1, glutamine synthetase gene.