Table 2.

Univariate Association Between Patient Characteristics and Survival

Characteristic	HR	95% CI	P
Mean glucose			.001
Quartile one, n = 46	Reference
Quartile two, n = 50	1.30	0.86 to 1.95
Quartile three, n = 48	1.56	1.02 to 2.37
Quartile four, n = 47	2.06	1.35 to 3.14
Mean daily dexamethasone dose, per 10 mg/d	1.29	1.14 to 1.45	< .0001
Age, per 10 years	1.50	1.30 to 1.73	< .0001
KPS, per 10 points	0.82	0.71 to 0.94	.006
Race, white v other	1.47	0.84 to 2.59	.181
Sex, male v female	1.04	0.77 to 1.41	.794
Biopsy v surgery	1.34	0.91 to 1.98	.133
Trial			.908
Penicillamine	Reference
Carboxyamido-triazole	0.95	0.63 to 1.44
Suramin and XRT	1.20	0.79 to 1.81
Gadolinium-texaphyrin	0.83	0.35 to 1.97
Cox-2 inhibitor	0.99	0.62 to 1.57

NOTE. The time-weighted mean glucose values for quartiles one to four are < 94, 94 to 109, 110 to 137, and > 137 mg/dL, respectively.

Abbreviations: HR, hazard ratio; KPS, Karnofsky performance score; XRT, radiation therapy.