Table 2.
Term | Coefficient | LR testa | P valuea | |
---|---|---|---|---|
Survivorship b | Intercept | −0.605 ± 0.094 | - | |
Secondary dose (750 iL3s) | −1.17 ± 0.17 | 34.38 | <0.001 | |
Time (Day 21 p.s.i.) | −0.624 ± 0.106 | 55.13 | <0.001 | |
Primary dose (30 S. ratti iL3s)c | −0.385 ± 0.126 | |||
Primary dose (750 S. ratti iL3s)c | −2.54 ± 0.21 | 168.13 | <0.001 | |
Secondary dose × Time | −3.96 ± 0.32 | 198.50 | <0.001 | |
Fecundity d | Intercept | 2.27 ± 0.31 | ||
Secondary dose (750 iL3s) | 0.87 ± 0.18 | 21.01 | <0.001 | |
Time (Day 21 p.s.i.) | −3.45 ± 0.63 | 39.40 | <0.001 | |
Primary spp. (N. brasiliensis) | 0.375 ± 0.366 | |||
Primary spp. (S. venezuelensis) | 0.755 ± 0.366 | |||
Primary spp. (S. ratti) | −0.157 ± 0.367 | 13.18 | <0.01 | |
Time × Primary spp. (N. brasiliensis) | 2.13 ± 0.70 | |||
Time × Primary spp. (S. venezuelensis) | 2.04 ± 0.70 | |||
Time × Primary spp. (S. ratti) | 3.15 ± 0.82 | 15.31 | <0.01 |
Likelihood ratio test presented for deletion of individual terms. For factors, tests refer to simultaneous deletion of all factor levels.
2 × log-likelihood = −318.31 with 50 residual degrees of freedom, overdispersion parameter k = 29.6 ± 14.5.
Factor levels for primary dose were grouped such that animals receiving either PBS, N. brasiliensis or S. venezuelensis in a primary infection were compared with those receiving 30 and 750 S. ratti iL3s as a primary infection.
2 × log-likelihood = −560.87 with 40 residual degrees of freedom, overdispersion parameter k = 2.83 ± 0.63.