Table 4.
The association between S. ratti fecundity and immune parameters
| Term | Coefficient | LR testa | P valuea | |
|---|---|---|---|---|
| IgG1 b | Intercept | 2.06 ± 0.35 | ||
| Time (Day 21 p.s.i.) | −3.48 ± 0.67 | 11.67 | <0.001 | |
| Secondary dose (750 iL3s) | 0.723 ± 0.195 | 12.87 | <0.001 | |
| Primary spp. (N. brasiliensis) | 0.390 ± 0.346 | - | ||
| Primary spp. (S. venezuelensis) | 0.759 ± 0.346 | - | ||
| Primary spp. (S. ratti) | 0.241 ± 0.444 | 12.12 | <0.01 | |
| Time × Primary spp. (N. brasiliensis) | 2.09 ± 0.68 | - | ||
| Time × Primary spp. (S. venezuelensis) | 2.19 ± 0.69 | - | ||
| Time × Primary spp. (S. ratti) | 2.64 ± 0.85 | 12.64 | <0.01 | |
| IgG1 | −0.320 ± 0.184 | 0.23 | 0.63 | |
| Time × IgG1 | 0.686 ± 0.297 | 4.99 | <0.05 | |
| IL4 c | Intercept | 1.28 ± 0.42 | ||
| Time (Day 21 p.s.i.) | −3.26 ± 0.73 | 7.40 | <0.01 | |
| Secondary dose (750 iL3s) | 0.988 ± 0.261 | 14.66 | <0.001 | |
| Primary spp. (S. ratti) | 1.57 ± 0.63 | 1.08 | 0.30 | |
| Time × Primary spp. (S. ratti) | 2.13 ± 0.94 | 5.50 | <0.05 | |
| IL4 MLN | −1.30 ± 0.43 | 1.015 | 0.31 | |
| Time × IL4 MLN | 2.23 ± 0.54 | 19.17 | <0.001 | |
| IL13 d | Intercept | 3.16 ± 0.23 | ||
| Time (Day 21 p.s.i.) | −5.02 ± 0.62 | 7.40 | <0.01 | |
| Secondary dose (750 iL3s) | 0.724 ± 0.163 | 19.10 | <0.001 | |
| Primary spp. (S. ratti) | −0.510 ± 0.170 | 1.08 | 0.30 | |
| Time × Primary spp. (S. ratti) | 3.46 ± 0.58 | 42.55 | <0.001 | |
| IL13 MLN | −0.479 ± 0.152 | 0.41 | 0.52 | |
| Time × IL13 MLN | 2.07 ± 0.53 | 16.25 | <0.001 |
a
Likelihood ratio test presented for deletion of individual terms. For factors, tests refer to simultaneous deletion of all factor levels.
b
2 × log-likelihood = −555.89 with 38 residual degrees of freedom, overdispersion parameter k = 3.18 ± 0.73
c
2 × log-likelihood = −168.595 with 10 residual degrees of freedom, overdispersion parameter k = 3.18 ± 0.73
d
2 × log-likelihood = −106.54 with 6 residual degrees of freedom, overdispersion parameter k = 33.1 ± 18.9