Table 3.
Odds Ratios for Patient and Tumor Characteristics by Biologic Subtype
| Variable Category | Triple Negative |
HER2 |
Luminal B (referent) | Luminal A |
|||
|---|---|---|---|---|---|---|---|
| OR | P | OR | P | OR | P | ||
| N1 v N2 | |||||||
| Type, ductal v lobular* | 9.17 | < .0001 | 10.61 | < .0001 | 1.0 | 0.38 | < .0001 |
| Size, > 2 v ≤ 2 cm | 1.40 | .0450 | 1.13 | .5436 | 1.0 | 0.73 | .0408 |
| Grade, 1 v 2 | 0.13 | .0447 | 0.09 | .018 | 1.0 | 3.74 | < .0001 |
| Grade, 3 v 1 + 2 | 14.50 | < .0001 | 4.74 | < .0001 | 1.0 | 0.05 | < .0001 |
| Vascular invasion, positive v negative | 1.11 | .5612 | 1.22 | .3871 | 1.0 | 0.46 | .0004 |
| MIB-1 index, high v low | 1.52 | .4270 | 2.63 | .0683 | 1.0 | NA | |
| p53, positive v negative | 4.19 | < .0001 | 4.19 | < .0001 | 1.0 | 0.23 | < .0001 |
| PR, positive v negative | NA | NA | 1.0 | 1.50 | .0655 | ||
Abbreviations: OR, odds ratio; NA, not applicable; PR, progesterone receptor.
*
Includes lobular mixed and pure lobular carcinomas.