Table 1.

Relative Risk of Death From All Causes in First 5 Years After Wilms Tumor Diagnosis

Characteristic	No. of Patients	Person-Years	No. of Deaths	No. of Expected Deaths	SMR*	95% CI	RR†	95% CI
All patients	6,185	27,238	819	33.8	24.3	22.6 to 26.0
Sex
Male	2,958	13,034	382	19.1	20.0	18.0 to 22.1	1.0
Female	3,227	14,204	437	14.6	29.8	27.1 to 32.8	1.02	0.88 to 1.17
Age at diagnosis, years
0-4	4,720	21,056	548	32.1	17.1	15.7 to 18.6	1.0
5-9	1,279	5,409	226	1.4	165.1	144.3 to 188.1	1.62	1.38 to 1.90
10-15	186	774	45	0.3	131.8	96.1 to 176.4	2.14	1.57 to 2.91
Year of diagnosis
1969-1974	557	2,336	112	4.4	25.7	21.1 to 30.9	1.0
1975-1979	908	3,862	166	6.0	27.7	23.7 to 32.3	0.77	0.61 to 0.98
1980-1984	1,475	6,489	204	8.4	24.2	21.0 to 27.8	0.59	0.47 to 0.75
1985-1989	1,560	7,022	180	8.1	22.3	19.2 to 25.8	0.49	0.38 to 0.62
1990-1995	1,685	7,530	157	6.9	22.7	19.3 to 26.5	0.37	0.29 to 0.47
Histology
Favorable	5,199	23,759	458	29.7	15.4	14.0 to 16.9	1.0
Anaplasia	380	1,217	175	1.0	183.2	157.0 to 212.4	6.72	5.63 to 8.04
CCSK	200	844	56	1.3	43.9	33.1 to 57.0	3.44	2.60 to 4.56
RTK	105	176	80	0.3	229.6	182.1 to 285.8	23.07	18.04 to 29.48
Other/unknown	301	1,242	50	1.5	33.5	24.9 to 44.2	1.73	1.29 to 2.32

Abbreviations: SMR, standardized mortality ratio; RR, rate ratio; CCSK, clear cell sarcoma of the kidney; RTK, rhabdoid tumor of the kidney.

^*Estimated SMRs are univariate.

^†RRs come from a joint Cox proportional hazards model including all covariates shown.