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. 2009 Jan 12;27(8):1304–1309. doi: 10.1200/JCO.2008.18.6981

Table 5.

Relative Rates of Mortality From All Causes, Late Effects, and SMNs Among 5-Year Survivors

Characteristic No. of Patients Cause of Death
All Causes
Effects of Treatment
SMNs
No. of Deaths RR 95% CI No. of Deaths RR 95% CI No. of Deaths RR 95% CI
Total 4,972 159 62 27
Sex
    Male 2,372 83 1.00 30 1.00 18 1.00
    Female 2,600 76 0.79 0.58 to 1.08 32 0.93 0.57 to 1.54 9 0.43 0.19 to 0.96
Age at diagnosis, years
    0-4 3,874 98 1.00 38 1.00 14 1.00
    5-9 971 46 1.97 1.39 to 2.80 20 2.23 1.30 to 3.84 11 3.46 1.57 to 7.64
    10-15 127 15 5.03 2.91 to 8.67 4 3.38 1.20 to 9.50 2 4.57 1.03 to 20.17
Year of diagnosis
    1969-1974 436 21 1.00 18 1.00 9 1.00
    1975-1979 700 37 1.08 0.65 to 1.81 18 1.07 0.52 to 2.21 8 0.79 0.29 to 2.19
    1980-1984 1,203 42 1.05 0.62 to 1.77 15 0.83 0.37 to 1.86 6 0.59 0.19 to 1.84
    1985-1989 1,296 28 0.93 0.52 to 1.68 7 0.57 0.21 to 1.56 2 0.36 0.07 to 1.90
    1990-1995 1,337 21 1.13 0.59 to 2.15 4 0.65 0.19 to 2.22 2 0.76 0.13 to 4.49

Abbreviations: SMN, second malignant neoplasm; RR, rate ratio.