Figure 2.
(A) Detection of Mamu-A*01 DNA in tail samples from 13 Tg mice by PCR. Cont symbolizes control transgene Mamu-A*01/Kb plasmid DNA template. M represents 1 kb DNA ladder molecular size marker. (B) Detection of cell surface expression of Mamu-A*01/Kb MHC antigen in spleen cells. Splenocytes from DKO (left) mice and Mamu-A*01/Kb Tg (right) mice were stained with FITC-conjugated MAb W6/32 followed by flow cytometry. Splenocytes were also treated with 15 ng/ml IFN-γ for 16 hrs to enhance MHC antigen expression levels.