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. Author manuscript; available in PMC: 2010 Feb 1.
Published in final edited form as: Biomaterials. 2008 Dec 7;30(6):1232–1245. doi: 10.1016/j.biomaterials.2008.10.064

Fig. 1.

Fig. 1

Dose dependent effect of various poloxamers on luciferase gene expression in skeletal (tibialis anterior) muscle of BALB/c mice after single i.m. injection of 10 μg plasmid DNA in 50 μl HBSS solution with or without block copolymers (5 mice/group). Muscles tissue was harvested on day 4 after i.m. injection and luciferase activity was measured using a standard procedure described in the Methods section. Data are mean ± SEM (n = 5).The P values were obtained by the means of the Student's t test following logarithmic transformation of the data. Each P value corresponds to the comparison of naked DNA versus DNA formulated with P85: * p < 0.05