Table 3.
Simulation Models for Type I Error Testing
Scenario | Model | ||||||||
---|---|---|---|---|---|---|---|---|---|
1 | No polygenic or no major X-linked QTL effecta | 0 | 0 | 0 | 40 | ||||
2 | No major X-linked QTL effect | 0 | 0 | 12 | 28 | ||||
3 | No polygenic effect but major X-linked QTL effect under DC | 4 | 2 | 0 | 36 | ||||
4 | No polygenic effect but major X-linked QTL effect under NDC | 4 | 8 | 0 | 36 | ||||
5 | Major X-linked QTL effect under DCb,c | 4 | 2 | 12 | 24 | ||||
6 | Major X-linked QTL effect under NDCb,c | 4 | 8 | 12 | 24 |
Major X-linked QTL effect means that there is X-linked linkage.
Admixture models with scenarios 5 and 6 for an X-linked single marker have p = r = 0.2 in one subpopulation and p = r = 0.5 in the other subpopulation.
Admixture models with scenarios 5 and 6 for an X-linked haplotype marker have p = 0.2, marker haplotype frequency distribution {0.25, 0.25, 0.25, 0.25} in one subpopulation and p = 0.5, marker haplotype frequency distribution {0.7, 0.1, 0.1, 0.1} in the other subpopulation.