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. 2009 Apr 10;84(4):431–444. doi: 10.1016/j.ajhg.2009.02.010

Table 3.

Simulation Models for Type I Error Testing

Scenario Model
σm2
σf2
σg2
σe2
1 No polygenic or no major X-linked QTL effecta 0 0 0 40
2 No major X-linked QTL effect 0 0 12 28
3 No polygenic effect but major X-linked QTL effect under DC 4 2 0 36
4 No polygenic effect but major X-linked QTL effect under NDC 4 8 0 36
5 Major X-linked QTL effect under DCb,c 4 2 12 24
6 Major X-linked QTL effect under NDCb,c 4 8 12 24
a

Major X-linked QTL effect means that there is X-linked linkage.

b

Admixture models with scenarios 5 and 6 for an X-linked single marker have p = r = 0.2 in one subpopulation and p = r = 0.5 in the other subpopulation.

c

Admixture models with scenarios 5 and 6 for an X-linked haplotype marker have p = 0.2, marker haplotype frequency distribution {0.25, 0.25, 0.25, 0.25} in one subpopulation and p = 0.5, marker haplotype frequency distribution {0.7, 0.1, 0.1, 0.1} in the other subpopulation.