Table 7.

Estimates of Within-Family Effect and Male X-Linked Genetic Variance for a Single Marker

D/Dmax		0		0.2		0.4
Scenario 5 and DC Test		βw	${\mathit{\sigma }}_{\mathit{qm}}^2$	βw	${\mathit{\sigma }}_{\mathit{qm}}^2$	βw	${\mathit{\sigma }}_{\mathit{qm}}^2$
	True value	0	4	0.875	3.84	1.75	3.36
With Parents Without Parents	Sample mean	0.011	4.11	0.873	3.86	1.739	3.43
	Standard deviation	0.006	1.07	0.009	1.06	0.009	1.01
	Sample mean	0.018	4.17	0.868	3.91	1.727	3.46
	Standard deviation	0.013	1.11	0.016	1.09	0.015	1.04
D/Dmax		0.6		0.8		1.0
Scenario 5 and DC Test		βw	${\mathit{\sigma }}_{\mathit{qm}}^2$	βw	${\mathit{\sigma }}_{\mathit{qm}}^2$	βw	${\mathit{\sigma }}_{\mathit{qm}}^2$
	True value	2.625	2.56	3.50	1.44	4.375	0
With Parents Without Parents	Sample mean	2.615	2.617	3.494	1.34	4.365	0.046
	Standard deviation	0.007	0.937	0.008	0.906	0.008	0.739
	Sample mean	2.582	2.71	3.481	1.59	4.343	0.052
	Standard deviation	0.012	0.991	0.014	0.977	0.012	0.871
D/Dmax		0		0.2		0.4
Scenario 6 and NDC Test		βw	${\mathit{\sigma }}_{\mathit{qm}}^2$	βw	${\mathit{\sigma }}_{\mathit{qm}}^2$	βw	${\mathit{\sigma }}_{\mathit{qm}}^2$
	True value	0	4	1.0	3.84	2.0	3.36
With Parents Without Parents	Sample mean	0.007	3.83	0.981	3.74	1.984	3.30
	Standard deviation	0.008	1.09	0.011	1.10	0.010	1.00
	Sample mean	0.015	3.65	0.976	3.71	1.980	3.26
	Standard deviation	0.014	1.16	0.018	1.13	0.016	1.06
D/Dmax		0.6		0.8		1.0
Scenario 6 and NDC Test		βw	${\mathit{\sigma }}_{\mathit{qm}}^2$	βw	${\mathit{\sigma }}_{\mathit{qm}}^2$	βw	${\mathit{\sigma }}_{\mathit{qm}}^2$
	True value	3.0	2.56	4.0	1.44	5.0	0
With Parents Without Parents	Sample mean	2.985	2.58	3.986	1.48	4.992	0.031
	Standard deviation	0.009	0.928	0.009	0.905	0.012	0.731
	Sample mean	2.975	2.51	3.974	1.51	4.983	0.040
	Standard deviation	0.013	0.989	0.014	0.985	0.012	0.819

The simulation was based on 5000 replicates of 250 families with four offspring, MAF as 0.2 for the tested marker and X-linked QTL, and D_max = 0.16.