Table 1.
Eleven Significant SNPs with the Same Effect in the Discovery Group and the First Replication Set
SNP | Chr. | Gene | p Value (DG)a | p Value (RS1)b | Homogeneity Testc | p Value Common Genotype Effectc | OR [95% CI]c |
---|---|---|---|---|---|---|---|
rs3914132 | 7q22.1 | RELN | 1.00 × 10−4 | 0.003 | 0.403 | 1.22 × 10−6 | 1.631 [1.335–1.993] |
rs1112578 | 2q32.2 | 2.80 × 10−4 | 0.004 | 0.493 | 4.34 × 10−6 | 0.691 [0.590–0.810] | |
rs4667276 | 2q32.2 | 0.001 | 0.002 | 0.690 | 6.91 × 10−6 | 0.697 [0.594–0.817] | |
rs17761499 | 16q23.2 | CDYL2 | 8.89 × 10−5 | 0.017 | 0.200 | 1.05 × 10−5 | 1.470 [1.237–1.748] |
rs11243426 | 9q34.13 | 0.002 | 0.016 | 0.463 | 1.11 × 10−4 | 1.409 [1.183–1.679] | |
rs4603268 | 11q21 | MAML2 | 0.002 | 0.033 | 0.347 | 2.42 × 10−4 | 1.367 [1.156–1.617] |
rs2246288 | 10q26.3 | INPP5A | 0.006 | 0.016 | 0.766 | 2.56 × 10−4 | 0.683 [0.556–0.840] |
rs4246059 | 6p25.2 | MYLK4 | 0.006 | 0.015 | 0.686 | 2.57 × 10−4 | 1.335 [1.143–1.560] |
rs10485428 | 6q12 | BAI3 | 0.003 | 0.039 | 0.345 | 5.23 × 10−4 | 1.671 [1.245–2.244] |
rs670358 | 11q13.1 | 0.028 | 0.022 | 0.909 | 0.001 | 0.670 [0.522–0.860] | |
rs2330247 | 21q22.3 | 0.022 | 0.046 | 0.773 | 0.002 | 0.723 [0.585–0.893] |
p value in the discovery group.
p value in the first replication set.
Combined data of discovery group and first replication set.