Table 3.

Allelic Heterogeneity in the Complete Belgian-Dutch Population

chr7q22.1 SNPs	p Valuea	LD with rs3914132b		Single-Locus Test when SNP Added to rs3914132	Single-Locus Test when rs3914132 Added to SNP	Single-Locus Test when SNP Added to rs3914132 and rs7791481
		D′	r2
rs17290575	0.020	0.490	0.213	0.661	1.92 × 10−5	0.361
rs262341	0.001	1.000	0.190	0.034	1.82 × 10−5	0.162
rs2299383	0.002	0.807	0.386	0.099	5.39 × 10−5	0.969
rs262355	0.040	0.874	0.148	0.257	4.92 × 10−6	0.502
rs17133096	0.032	0.572	0.005	0.087	1.57 × 10−6	0.142
rs11761011	0.031	0.598	0.014	0.076	1.99 × 10−6	0.169
rs39335	0.001	0.926	0.593	0.903	3.65 × 10−4	0.599
rs39346	0.008	1.000	0.085	0.115	7.34 × 10−6	0.326
rs39350	1.11 × 10−4	1.000	0.161	0.020	2.84 × 10−4	0.189
rs39374	1.63 × 10−5	1.000	0.135	0.014	0.001	0.214
rs12536007	0.023	1.000	0.028	0.060	4.46 × 10−6	0.121
rs39395	1.56 × 10−5	1.000	0.399	0.054	7.89 × 10−4	0.866
rs39399	2.86 × 10−5	1.000	0.175	0.027	3.21 × 10−4	0.309
rs13223714	0.014	1.000	0.090	0.002	1.26 × 10−7	0.384
rs39401	8.05 × 10−4	1.000	0.131	0.062	3.37 × 10−5	0.315
rs7791481	0.001	0.439	0.004	8.75 × 10−4	1.11 × 10−6	NA
rs2237641	0.021	1.000	0.024	4.71 × 10−4	6.03 × 10−8	0.213
rs3914129	0.018	1.000	0.190	0.325	3.09 × 10−5	0.980
rs3914132	1.23 × 10−6	NA	NA	NA	NA	NA
rs802786	0.003	0.890	0.792	0.229	4.50 × 10−5	0.277

NA denotes not applicable

^ap value with the discovery group and first replication set (complete Belgian-Dutch population) lumped together.

^bValues based on HapMap release 21a, Phase II.