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. 2008 Nov 17;83(5):643–648. doi: 10.1016/j.ajhg.2008.10.010

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© 2008 The American Society of Human Genetics. Published by Elsevier Ltd. All right reserved.

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The Families' Pedigree and Haplotype along the Critical Region on Chromosome 16

(A) Family 1 pedigree and their haplotype along the critical region on chromosome 16. Patients' symbols are filled. Numbered symbols represent individuals whose DNA samples were available for analysis. The polymorphic microsatellite markers and their chromosomal locations (in Mb) are given in the upper-left panel. C16 _65.77 stands for hg18_chr16:65767359-65767624, C16_67.21 stands for hg18_chr16:67214180-67214437, C16_68.20 stands for hg18_ chr16:68218628-68218887, C16_69.20 stands for hg18_chr16:69227890-69228133, and C16_73.87 stands for hg18_chr16:73875745-73875997.

(B) Family 2 pedigree. The asterisk represents an individual whose family name is identical to that of family 1.

(C) Family 3 pedigree. The polymorphic microsatellite markers and their location are given at the upper-left and upper-right panel, for family 2 and family 3, respectively.