Table 1.

The Parameters Estimated from Experimental Data: The Mean Heteroplasmy, p₀, and the b Parameter Calculated from the Variance and the p Value Calculated from the KS Test

Organism	Lineage	Sample	Generations	Mean Heteroplasmy, p0	Variance	N	b	KS Test p Value
Humans
	N/A	primary oocytes	-	0.1264	0.01432	82	0.8705	0.827
Mice
	515	tail biopsy	1	0.051	0.00240	41a	0.9505	0.646
	515	mature oocytes	-	0.047	0.00646	31	0.8558	0.049∗
	517	tail biopsy	1	0.076	0.00447	43	0.9363	0.75
	517	mature oocytes	-	0.094	0.0119	26	0.8604	0.834
	603A	mature oocytes	-	0.009	0.000185	49	0.9793	0.681
	603A	primary oocytes	-	0.011	0.00023	49a	0.9789	0.037∗
	603B	mature oocytes	-	0.031	0.00098	31	0.9674	0.435
	603B	primary oocytes	-	0.025	0.000638	46a	0.9738	0.223
Drosophila mauritiana
	H1	unfertilized eggs	30	0.4150	0.18670	60	0.2310	0.004∗∗
	H1-31M		3	0.1784	0.00952	59	0.9350	0.587
	H1-18D		3	0.4763	0.01711	31	0.9314	0.993
	H1-12B		5	0.8155	0.02791	52	0.8146	0.865
	G20-5		3	0.3250	0.01257	55	0.9430	0.922
	G71-12		3	0.5834	0.01804	50	0.9258	0.542
Drosophila simulans
	6YF16		3	0.1270	0.0096	44	0.9131	0.79

The “generations” column gives the number of organism generations, and thus this value is not given for samples of mature oocytes or primary oocytes. The p₀ parameter is obtained from the average of the heteroplasmy measurements. N is the number of samples from the experiment. The p value is the level of significance for the null hypothesis that the experimental heteroplasmy distribution matches the Kimura distribution. The asterisks indicate significance levels: ^∗ 0.01 < p < 0.05 and ^∗∗ p < 0.01.

^aIn these three cases, we found discrepancies between the number of samples listed in the cited paper²¹ and the number of samples actually given in the data set.