Table 2.
Two-Point LOD Score for Linkage between the HSP Locus and Markers on Chromosome 3q24-q26
| Marker | Position |
Za at θ = 0 | |
|---|---|---|---|
| cM | Mb | ||
| D3S1764 | 152.62 | 140.67 | −7.710 |
| D3S1512 | 158.38 | 145.82 | −7.547 |
| D3S2326 | 159.8 | 145.69 | −1.532 |
| D3S2394 | 160.4 | 147.03 | 3.035 |
| D3S1744 | 161.04 | 148.57 | 3.569 |
| D3S1746 | 169.6 | 153.21 | 5.085 |
| D3S1545 | 173.72 | 163.15 | 5.069 |
| D3S1543 | 173.84 | 162.15 | 5.068 |
| D3S3052 | 174.94 | 165.68 | 5.045 |
| D3S1763 | 176.54 | 168.72 | 4.975 |
| D3S3053 | 181.87 | 173.23 | 0.797 |
a
A gene frequency of 0.0001 and a penetrance of 90% were assumed for the disease locus. Marker order and genetic distances were based on the chromosome 3 genetic map of the Center for Medical Genetics at the Marshfield Medical Research Foundation.