Table 3.
Dose–response relationship of clusters studied in more than 10 articles; results are given in % per THC dose group for each cluster and listed with their functional domain (grey)
<7 mg | 7–18 mg | >18 mg | |||||||
---|---|---|---|---|---|---|---|---|---|
Domain cluster | – | = | + | – | = | + | – | = | + |
Autonomic | |||||||||
Heart rate | 0 | 22 | 78 | 0 | 1 | 99 | 2 | 0 | 98 |
Motor | |||||||||
Motor control | 71 | 29 | 0 | 50 | 50 | 0 | 27 | 73 | 0 |
Visuomotor control | 68 | 32 | 0 | 64 | 36 | 0 | 19 | 81 | 0 |
Memory | |||||||||
Auditory/verbal memory delayed recall | 23 | 77 | 0 | 63 | 38 | 0 | 78 | 22 | 0 |
Auditory/verbal immediate recall | 50 | 50 | 0 | 75 | 25 | 0 | 45 | 55 | 0 |
Attention | |||||||||
DSST-like | 31 | 69 | 0 | 50 | 50 | 0 | 47 | 53 | 0 |
Focused selective attention | 57 | 43 | 0 | 33 | 67 | 0 | 14 | 86 | 0 |
Reaction time | 46 | 54 | 0 | 52 | 45 | 3 | 47 | 53 | 0 |
Executive | |||||||||
Inhibition | 50 | 50 | 0 | 52 | 48 | 0 | 57 | 43 | 0 |
Working memory | 52 | 48 | 0 | 42 | 58 | 0 | 9 | 91 | 0 |
Reasoning/association | 33 | 67 | 0 | 37 | 63 | 0 | 43 | 57 | 0 |
Subjective experiences | |||||||||
Scale aggression | 20 | 80 | 0 | 24 | 71 | 5 | 40 | 50 | 10 |
Scale alertness | 43 | 50 | 7 | 43 | 50 | 7 | 35 | 51 | 14 |
Scale anxiety | 11 | 83 | 6 | 35 | 62 | 4 | 33 | 63 | 4 |
Scale calmness | 10 | 60 | 30 | 31 | 50 | 19 | 26 | 48 | 26 |
Scale craving | 53 | 22 | 25 | 61 | 11 | 28 | 20 | 20 | 60 |
Scale drug effect | 12 | 32 | 56 | 4 | 18 | 78 | 3 | 21 | 76 |
Scale high | 0 | 6 | 94 | 0 | 0 | 100 | 0 | 5 | 95 |
Scale mood | 29 | 61 | 10 | 17 | 66 | 17 | 19 | 59 | 22 |
Scale psychotomimetic | 83 | 17 | 0 | 81 | 19 | 0 | 76 | 24 | 0 |
Scale symptoms | 64 | 36 | 0 | 58 | 37 | 5 | 41 | 59 | 0 |
DSST, digit symbol substitution test.