Table 3.
2001 (n = 2399) | 2004 (n = 2136) | |||||
---|---|---|---|---|---|---|
First-generation antipsychotic | n (%) | Mean doses (SD), mg | CPZ eq (SD), mg day−1 | n (%) | Mean doses (SD), mg | CPZ eq (SD), mg day−1 |
Haloperidol | 691 (28.8) | 15.9 (11.8) | 793.9 (587.7) | 387 (18.1) | 14.3 (10.3) | 713.5 (515.0) |
Chlorpromazine | 561 (23.4) | 231.0 (201.3) | 231.0 (201.3) | 349 (16.3) | 213.8 (204.9) | 213.8 (204.9) |
Levomepromazine | 247 (10.3) | 77.5 (90.9) | 77.5 (90.9) | 165 (7.7) | 83.9 (85.7) | 83.9 (85.7) |
Sulpiride | 233 (9.7) | 606.4 (370.4) | 303.2 (185.2) | 178 (8.3) | 656.7 (411.2) | 328.4 (205.6) |
Trifluoperazine | 115 (4.8) | 17.4 (10.1) | 348.1 (201.3) | 41 (1.9) | 13.5 (10.5) | 270.0 (210.0) |
Second-generation antipsychotic | ||||||
Risperidone | 473 (19.7) | 4.7 (2.6) | 235.0 (130.0) | 631 (29.5) | 4.7 (2.4) | 235.0 (120.0) |
Clozapine | 348 (14.5) | 130.1 (77.7) | 260.2 (155.3) | 340 (15.9) | 120.1 (60.3) | 240.2 (120.6) |
Zotepine | 137 (5.7) | 181.7 (115.3) | 272.5 (173.3) | 10 (0.5) | 112.0 (31.6) | 168.0 (47.4) |
Olanzapine | 115 (4.8) | 16.3 (6.0) | 326.0 (120.0) | 226 (10.6) | 15.3 (6.1) | 306.0 (122.0) |
Quetiapine | 86 (3.6) | 444.8 (251.5) | 578.3 (326.9) | 168 (7.9) | 420.3 (250.0) | 546.4 (325.0) |
CPZ eq, chlorpromazine equivalents; SD, standard deviation.