Table 5.
Factors associated with high-dose antipsychotic use in the whole sample in 2004
| B | SE | Wald | P | OR* | 95.0% CI | |
|---|---|---|---|---|---|---|
| Age | −0.02 | 0.01 | 4.25 | 0.04 | 0.98 | 0.97, 0.99 |
| Gender | 0.20 | 0.19 | 1.14 | NS | 1.22 | 0.85, 1.76 |
| First admission | 0.68 | 0.28 | 5.89 | 0.015 | 0.51 | 0.29, 0.88 |
| Delusion | 0.41 | 0.22 | 3.32 | NS | 1.50 | 0.97, 2.33 |
| Hallucination | 0.34 | 0.20 | 2.89 | NS | 1.41 | 0.95, 2.08 |
| Disorganized speech | 0.26 | 0.20 | 1.70 | NS | 1.29 | 0.88, 1.90 |
| Negative symptoms | −0.27 | 0.20 | 1.83 | NS | 0.77 | 0.52, 1.13 |
| Aggression (physical) | 0.37 | 0.25 | 2.22 | NS | 1.44 | 0.89, 2.33 |
| Depot antipsychotic | −0.06 | 0.36 | 0.03 | NS | 0.94 | 0.46, 1.90 |
| FGA | 1.07 | 0.27 | 15.28 | <0.001 | 2.92 | 1.71, 5.01 |
| SGA | −0.08 | 0.23 | 0.12 | NS | 0.92 | 0.59, 1.45 |
| Antipsychotic polytherapy | 4.59 | 6.61 | 0.48 | NS | 98.29 | 0.00, 200.45 |
*
Analysis is based on multivariate logistic regression modelling. CI, confidence interval; FGA, first-generation antipsychotic; OR, odds ratio; SGA, second-generation antipsychotic.