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. Author manuscript; available in PMC: 2010 Feb 1.
Published in final edited form as: Biol Psychiatry. 2008 Aug 16;65(3):249–257. doi: 10.1016/j.biopsych.2008.07.005

Figure 4.

Figure 4

RU38486-mediated disruption of a traumatic memory is selective for the reactivated memory and does not interfere with the stability of another established memory. Groups of rats were trained in both IA and in FC. IA retention is expressed as mean latencies ± s.e.m., FC retention is expressed as mean % freezing ± s.e.m.. (A) Rats underwent reactivation of IA but not FC: Groups of rats systemically injected (↑) with 30 mg/Kg of RU38486 (n = 8) or Veh (n = 6) immediately after IA reactivation (Test 1) and re-tested 48 hours later for both IA (IA Test 2; *p < 0.05) and FC (no effect) retentions. (B) Rats underwent reactivation of FC but not IA: Groups of rats systemically injected (↑) with 30 mg/Kg of RU38486 (n = 8) or Veh (n = 8) immediately after FC Test 1 and tested 48 hours later for both IA (no effect) and FC (FC Test 2, *p < 0.05).