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. 2009 Apr 24;5(4):e1000367. doi: 10.1371/journal.pcbi.1000367

Figure 1. The pore model.

Figure 1

(A) Two opposing RyR1 monomers shown in cartoon representation. The selectivity filter (the motif 4894GGGIGDE) is shown in yellow. (B) Selectivity filter region of two opposing RyR1 monomers shown in stick representation. The sequence of the fragment is shown along the path of the ions. The molecular surface of the luminal face (C) and the cytoplasmic face (D) of RyR1 pore tetramer. Negative residues are shown in red while positive residues are shown in blue and the neutral residues are shown in white. This figure was created using PyMOL (http://pymol.sourceforge.net/).