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. 2009 Apr 24;5(4):e1000367. doi: 10.1371/journal.pcbi.1000367

Figure 2. Ion permeation properties of RyR1-WT (top), RyR1-D4899Q (middle), and RyR1-G4898R (bottom) ion channels.

Figure 2

Upper traces represent single channel currents (openings shown as downward deflections from the closed state (c–) recorded in symmetrical 250 mM KCl and 5 µM free Ca2+ cis. Bottom traces represent single channel currents recorded at 0 mV following the addition of 10 mM trans Ca2+.