. 2009 Apr 24;5(4):e1000367. doi: 10.1371/journal.pcbi.1000367

Table 3. Ion occupancy in the selectivity filter in different simulations.

Simulation	Number of ions¹			Total number of ions in the selectivity filter	R^‡
	Ca²⁺	K⁺	Na⁺
RyR1-WT CaCl₂	3.68±1.15	-	-	3.68±1.15	-
RyR1-WT KCl	-	6.94±1.08	-	6.94±1.08	-
RyR1-WT CaCl₂/KCl	2.94±0.45	1.13±0.58	-	4.07±0.95	11.31±5.63
RyR1-WT NaCl/KCl	-	3.2	2	5.2	2.2
RyR1-D4899Q CaCl₂/KCl	1.31±0.31	1.67±0.74	-	2.97±0.68	3.11±1.62
RyR1-D4899Q KCl	-	2.97±0.4	-	2.97±0.4	-
RyR1-G4898R CaCl₂/KCl	2.26±0.15	1.75±0.27	-	4.01±0.22	4.48±0.9
RyR1-G4898R KCl	-	4.67±0.95	-	4.67±0.95	-

In the selectivity filter, which is the shaded region shown in Figure 4 and Figure 5.

‡: Ratio of preferential occupancy of ion1 over ion2 normalized by total number of ions present in each species.