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. Author manuscript; available in PMC: 2009 Apr 13.
Published in final edited form as: Angew Chem Int Ed Engl. 2008;47(22):4119–4121. doi: 10.1002/anie.200800069

Figure 2. Methods of increasing MRSw sensitivity.

Figure 2

a) Decrease in particle concentration. Anti-Tag forms bridges between larger MPs. b) Magnetic field enhanced target aggregation. A magnetic field (+H) produces magnetic attractions between MPs that result in aggregation. In the presence of anti-Tag (top) the aggregate is maintained when the field is removed (−H) and a high T2 results. c) Valency enhanced aggregation. The addition of an anti-Fc antibody permits anti-Tag to bind more than two MPs simultaneously.