Skip to main content

View full-text article in PMC

. Author manuscript; available in PMC: 2009 Dec 25.

Published in final edited form as: J Med Chem. 2008 Dec 25;51(24):7788–7799. doi: 10.1021/jm800781a

Table 3.

Comparison of uptake of [¹⁸F]1-[¹⁸F]4 in SERT-rich brain regions to cerebellum uptake at 115 and 215 minutes post-injection.

Brain	115 min					215 min
Region	[¹⁸F]1^a	[¹⁸F]1	[¹⁸F]2	[¹⁸F]3	[¹⁸F]4	[¹⁸F]1	[¹⁸F]2	[¹⁸F]3	[¹⁸F]4
Caudate	1.6	1.4	1.5	1.2	1.4	1.5	1.6	1.2	1.7
Putamen	1.6	1.7	1.7	1.4	1.5	1.8	1.8	1.5	1.7
Thalamus	1.8	1.6	1.5	1.4	1.5	1.7	1.6	1.5	1.7
Midbrain	1.9	1.9	1.7	1.5	1.7	2.2	2.1	1.8	2.2
Pons	1.8	1.3	1.6	1.3	1.3	1.5	1.8	1.5	1.5
Medulla	1.3	1.5	1.5	1.5	1.5	1.7	1.7	1.8	1.8
Occipital	N/A	0.9	1.1	1.0	1.1	0.9	1.1	1.0	1.3
Frontal	1.2	1.0	1.0	0.8	1.0	1.1	1.1	1.0	1.0

^a

= HRRT awake rhesus study.