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. Author manuscript; available in PMC: 2009 Dec 25.
Published in final edited form as: J Med Chem. 2008 Dec 25;51(24):7788–7799. doi: 10.1021/jm800781a

Table 6.

Comparison of the uptake ratios between [18F]1 and [18F]19 for anesthetized and awake monkey studies at selected time points.a

Anesthetized
Awake
Brain 55 min
115 min
225 min
95 min
Region [18F]1 [18F]19 [18F]1 [18F]19 [18F]1 [18F]19 [18F]1 [18F]19
Caudate 1.1 1.1 1.4 1.7 1.6 2.5 1.5 2.0
Putamen 1.2 1.6 1.7 2.4 1.9 3.5 1.7 2.1
Thalamus 1.2 1.5 1.6 2.2 1.8 3.1 1.7 2.4
Midbrain 1.4 1.6 1.9 2.5 2.4 4.2 1.6 2.0
Pons 0.9 1.2 1.3 2.0 1.6 3.1 1.5 1.6
Medulla 1.1 1.5 1.5 2.1 1.9 3.0 1.1 1.5
a)

See Tables S6, S7, S12, and S14 for the complete data. Also see Figures S1, S2, S16, and S18.