Table 3.
Factors that mediate intracellular trafficking of chemokine receptors
Regulatory factors | Receptors | Reference |
---|---|---|
Multiple ligands | CXCR2, CXCR3, CCR3, CCR4 | [22,45,92,93,181] |
Cytoskeleton | ||
Actin | CXCR2, CCR5 | [94,96] |
Motor proteins | CXCR2 | [91] |
Length of ligand stimulation | CXCR2, CCR5 | [59,90] |
Rabs | ||
Rab4 | FPR | [66] |
Rab5 | CXCR2, CXCR4, CCR5 | [3,59] |
Rab7 | CXCR2 | [59] |
Rab11 | CXCR2, FPR | [59,66] |
β-Arrestin/recycling | FPR | [103,104] |