FIG. 4.

IFN-γ production by bison PBMC. Bison were vaccinated with saline only, 4.6 × 10¹⁰ CFU of RB51 or 7.4 × 10¹⁰ CFU of RB51+sodC,wboA (n = 8 animals/treatment). Cells were incubated at 37°C and 5% CO₂ for 72 h in the presence or absence of 10⁸ CFU of gamma-irradiated RB51. The results are expressed as mean net IFN-γ production (production in wells containing RB51 − production in wells without antigen). Means within a sampling time with different superscripts are significantly different (P < 0.05).