TABLE 3.
Similarity in DNA sequence between PE and PPE genes that are unique to a member of the MAC and their closest orthologue in other members of the complex or other mycobacterial species
| Gene | Unique PPE genes and closest orthologuesa
|
% Nucleotide sequence identity between genes from the following pairs:
|
Locus of non-MAC mycobacterial spp. with which homology exists | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| M. avium subsp. paratuberculosis | M. avium subsp. hominissuis | M. avium subsp. avium | M. intracellulare | M. avium subsp. paratuberculosis-M. avium subsp. hominissuis | M. avium subsp. paratuberculosis-M. avium subsp. avium | M. avium subsp. paratuberculosis-M. intracellulare | M. avium subsp. hominissui-M. avium subsp. avium | M. avium subsp. hominissui- M. intracellulare | M. avium subsp. avium-M. intracellulare | ||
| PPE | PPE33 | PPE4 | PPE33 | PPE18 | 53.8 | 53.7 | 50.2 | Rv1548c | |||
| PPE20 | PPE12 | PPE20 | PPE43 | 57.9 | 59.5 | 58.8 | Mt1850 | ||||
| PPE41 | PPE36 | PPE36 | PPE40 | 58.2 | 55.6 | 59.5 | Mt0269 | ||||
| PPE42 | PPE39 | PPE39 | PPE40 | 60.8 | 60.1 | 56.4 | Mt0269 | ||||
| PPE6 | PPE6 | PPE6 | PPE45 | 55.4 | 42.3 | 42.7 | Mt1745 | ||||
| PPE18 | PPE18 | PPE18 | PPE46 | 58.4 | 58.5 | 57.6 | Mt1850 | ||||
| PPE31 | PPE31 | PPE31 | PPE47 | 60.4 | 60.2 | 60.1 | Mul_2096 | ||||
| PPE18 | PPE18 | PPE18 | PPE44 | 58.4 | 58.4 | 58.5 | Mt1851 | ||||
| PPE18 | PPE18 | PPE18 | PPE43 | 58.3 | 58.3 | 58.1 | Mt1850 | ||||
| PPE21 | PPE21 | PPE21 | PPE48 | 61.9 | 61.9 | 61.9 | Mul_0947 | ||||
| PE | PE7 | PE7 | PE7 | PE11 | 63.0 | 64.0 | 64.0 | Rv1791 | |||
a
Unique PE and PPE genes are indicated in boldface.