TABLE 4.

Similarity in DNA sequence between PE and PPE genes that are missing from members of the MAC and their closest orthologues in other members of the complex

Orthologues of the missing PPE genesa				% Nucleotide sequence identity between genes from the following pairs:
M. avium subsp. paratuberculosis	M. avium subsp. hominissuis	M. avium subsp. avium	M. intracellulare	M. avium subsp. paratuberculosis-M. avium subsp. hominissuis	M. avium subsp. paratuberculosis-M. avium subsp. avium	M. avium subsp. paratuberculosis-M. intracellulare	M. avium subsp. hominissuis-M. avium subsp. avium	M. avium subsp. hominissuis-M. intracellulare	M. avium subsp. avium-M. intracellulare
PPE5	PPE26	PPE5	PPE5	58.3			55.6	52.7
PPE30	PPE39	PPE30	PPE30	59.4			59.6	61.8
PPE27	PPE27	PPE27	PPE47			59.6		59.9	59.8
PPE15	PPE15	PPE15	PPE36			55.6		54.6	54.3
PPE22	PPE11	PPE11	PPE11	57.0	56.2	54.2
PPE36	PPE39	PPE39	PPE36	61.8	65.3			62.0	62.7
PPE22	PPE22	PPE22	PPE48			61.1		60.6	60.5
PPE21	PPE21	PPE21	PP448			61.9		61.9	61.9

^aThe closest orthologues in other members of the complex are indicated in boldface.