. 2000 Jan 4;97(1):454–459. doi: 10.1073/pnas.97.1.454

Table 1.

Effects of drug administration on the power of otoacoustic emissions

Drug doses	Power (μPa²) in frequency band (kHz)				No. of ears
Drug doses	0.5–1.0	1.0–2.6	2.6–5.2	Total	No. of ears
Single acetylsalicylic acid
Control (total power above 3000 μPa²)	970 ± 100	2050 ± 150	760 ± 40	3780 ± 140	8
0 hr < t < 1 hr	675 ± 109^*	1499 ± 217^*	578 ± 110	2752 ± 379^*
1 hr < t < 2 hr	683 ± 98^*	1971 ± 244	822 ± 131	3478 ± 414
Control (total power below 3000 μPa²)	370 ± 120	760 ± 260	400 ± 120	1540 ± 320	5
0 hr < t < 1 hr	389 ± 103	1098 ± 113^*	686 ± 115^*	2177 ± 110^†
1 hr < t < 2 hr	506 ± 106	1337 ± 142^*	509 ± 102	2357 ± 216^*
Repeated acetylsalicylic acid
Control	790 ± 100	1970 ± 190	560 ± 50	3320 ± 230	16
3–7 days	752 ± 105	911 ± 302	233 ± 69^†	1896 ± 430
Single gentamicin
0 min < t < 20 min	749 ± 119	1690 ± 408	742 ± 98	3180 ± 548	8
20 min < t < 80 min	398 ± 112^*	995 ± 313	513 ± 164	1909 ± 533^*
80 min < t < 140 min	725 ± 110	1229 ± 227	621 ± 173	2581 ± 377
Single kanamycin
0 min < t < 20 min	658 ± 97	2288 ± 1077	400 ± 143	3346 ± 1308	4
20 min < t < 80 min	391 ± 111	1981 ± 138	592 ± 46^*	2932 ± 217
80 min < t < 140 min	365 ± 78^*	726 ± 889	296 ± 175	1388 ± 1112

Values of emission power are expressed as means ± SEM for the indicated number of ears. * Indicates a difference from the control value significant at the level P < 0.05; † indicates a difference from the control value significant at the level P < 0.001.