TABLE 2.

Selected genes or operons regulated by CepR2

Gene	Functiona	Transcriptional unitb	Change (fold) for K56-2cepR2b vs K56-2
			Microarrayc	qRT-PCR or RT-PCRd
BCAL1234	Putative heat shock Hsp20-related protein	BCAL1234-BCAL1233	−2.2 ± 0.5	−17.9 ± 21
BCAL1233	Putative heat shock protein		−2.0 ± 0.5
bclA	Lectin BclA	BCAM0186	2.9 ± 0.8	2.2 ± 0.1
cepR2	Orphan LuxR homolog CepR2		21.1 ± 3.4	170 ± 50
BCAM0189	Putative AraC-family regulatory protein		188 ± 46	26.7 ± 6.6
BCAM0190	Putative aminotransferase, class III		11.6 ± 0.9
BCAM0191	Putative nonribosomal peptide synthetase	BCAM0191-BCAM0190	9.5 ± 3.0	—e
BCAM0192	Conserved hypothetical protein	BCAM0192-BCAM0196	113 ± 27	—e
BCAM0193	Conserved hypothetical protein		171 ± 74
BCAM0194	Hypothetical protein		151 ± 48
BCAM0195	Putative nonribosomal peptide synthetase		58.3 ± 62.1
BCAM0196	Conserved hypothetical protein		80.5 ± 31.1
BCAM0199	Putative outer membrane efflux protein	BCAM0199-BCAM0202	2.5 ± 0.6	—e
BCAM0200	Putative secretion protein, HlyD family		8.4 ± 5.6
BCAM0201	Putative transporter		2.3 ± 0.8
BCAM0202	Hypothetical protein		1.8 ± 0.2
BCAM1290	RpiR family transcriptional regulator		−1.7 ± 0.2	−2.6 ± 2.0
BCAM1420	Putative multidrug efflux protein		−2.3 ± 1.2	−8.1 ± 0.3
BCAM2307	Zinc metalloprotease ZmpB		−1.7 ± 0.7	2.6 ± 1.2f
BCAS0293	Nematocidal protein AidA		1.7 ± 0.1	5.8 ± 2.9f
BCAS0409	Zinc metalloprotease ZmpA		1.6 ± 0.3	1.2 ± 0.1f

^aFunction derived from B. cenocepacia J2315 (33).

^bTranscriptional units were experimentally determined by RT-PCR.

^cUnless indicated otherwise, change (mean ± standard deviation) in 8-h cultures of K56-2cepR2b compared to 8-h cultures of K56-2 as determined by microarray analysis with at least two biological replicates.

^dChange (mean ± standard deviation) in 8-h cultures of K56-2cepR2b compared to 8-h cultures of K56-2 as determined by qRT-PCR.

^eExpression was measured by RT-PCR (see Fig. 3).

^fExpression was measured in cultures grown for 18 h.