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. 2009 Feb 25;83(9):4227–4235. doi: 10.1128/JVI.02578-08

FIG. 1.

FIG. 1.

The UR1 region of EBNA1 is highly conserved in the EBNA1 orthologs of EBV-like gammaherpesviruses. The region of aa 65 to 89 of EBNA1 from EBV strain B95-8 (accession no. YP_401677) are aligned with the corresponding region from the EBNA1 orthologs encoded by Cercopithecine herpesvirus 15 (accession no. YP_067973), cynomolgus EBV (accession no. BAB03281), and Cercopithecine herpesvirus 12 (accession no. AAA66373). In all four EBNA1 proteins, aa 75 to 85 are highly conserved, as indicated by the box, and also share identity with half of a C4 zinc finger found in the catalytic subunit of DNA polymerase δ from several eukaryotes (accession nos. NP_001087694, NP_001034899, XP_001641357, and XP_002008314).