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. Author manuscript; available in PMC: 2009 May 1.
Published in final edited form as: J Membr Biol. 2008 Jun 25;223(1):13–26. doi: 10.1007/s00232-008-9107-7

Figure 4. nAChR stability assays for non-lipid analog detergents.

Figure 4

A-SEC stability assay percent (%) peak areas for sucrose gradient detergent-solubilized membranes (white background) and ligand affinity-purified nAChR (black background) in: (a) Cymal-6 (sucrose gradient areas % peak areas: 68% dimer/32% monomer; affinity column % peak areas: 23% aggregate/57% dimer/20% monomer); (b) DDM (sucrose gradient % peak areas: 63% dimer/37% monomer; affinity column % peak areas: 30% aggregate/53% dimer/17% monomer), (c) LDAO (sucrose gradient % peak areas: 69% dimer/31% monomer; affinity column % peak areas: 33% aggregate/49% dimer/18% monomer) and (d) OG (sucrose gradient % peak areas: 83% dimer/17% monomer; affinity column % peak areas: 61% aggregate/39% dimer/0% monomer).