Table 5.
Delayed Entry Cox Proportional Hazards Models of Quartiles of Dietary Patterns and Risk of Overall Death by Selected Lifestyle Factors in the LACE Study
Factor | No. of Participants | No. of Events | Quartile |
P for Trend | P for Interaction | ||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Q1 HR | Q2 |
Q3 |
Q4 |
||||||||
HR | 95% CI | HR | 95% CI | HR | 95% CI | ||||||
Prudent dietary pattern | |||||||||||
Total physical activity* | |||||||||||
< median (46.7 MET-h/wk) | 948 | 122 | Referent | 0.61 | 0.37 to 1.00 | 0.83 | 0.52 to 1.34 | 0.38 | 0.19 to 0.77 | .03 | .12 |
≥ median (46.7 MET-hrs/wk) | 949 | 91 | Referent | 1.24 | 0.65 to 2.35 | 0.74 | 0.38 to 1.45 | 0.88 | 0.45 to 1.75 | .39 | |
BMI at enrollment† | |||||||||||
Not overweight/obese | 852 | 84 | Referent | 0.97 | 0.53 to 1.76 | 0.73 | 0.38 to 1.40 | 0.58 | 0.28 to 1.24 | .12 | .75 |
Overweight/obese (≥ 25 kg/m2) | 999 | 133 | Referent | 0.70 | 0.43 to 1.13 | 0.81 | 0.50 to 1.31 | 0.58 | 0.32 to 1.03 | .12 | |
Smoking status‡ | |||||||||||
Never | 1006 | 93 | Referent | 1.08 | 0.60 to 1.92 | 0.97 | 0.54 to 1.76 | 0.62 | 0.29 to 1.32 | .27 | .53 |
Ever | 892 | 120 | Referent | 0.61 | 0.36 to 1.02 | 0.67 | 0.40 to 1.10 | 0.51 | 0.29 to 0.92 | .04 | |
Western dietary pattern | |||||||||||
Total physical activity* | |||||||||||
< median (46.7 MET-h/wk) | 948 | 122 | Referent | 0.99 | 0.56 to 1.73 | 1.29 | 0.74 to 2.25 | 2.07 | 1.03 to 4.16 | .04 | .91 |
≥ median (46.7 MET-hrs/wk) | 949 | 91 | Referent | 0.84 | 0.46 to 1.56 | 1.16 | 0.63 to 2.13 | 1.23 | 0.59 to 2.56 | .48 | |
BMI at enrollment† | |||||||||||
Not overweight/obese | 852 | 84 | Referent | 0.76 | 0.40 to 1.44 | 1.28 | 0.70 to 2.36 | 1.36 | 0.58 to 3.20 | .33 | .69 |
Overweight/obese (≥ 25 kg/m2) | 999 | 133 | Referent | 0.98 | 0.57 to 1.67 | 1.14 | 0.66 to 1.97 | 1.64 | 0.86 to 3.11 | .13 | |
Smoking status‡ | |||||||||||
Never | 1006 | 93 | Referent | 1.36 | 0.76 to 2.44 | 1.24 | 0.65 to 2.37 | 2.14 | 0.95 to 4.79 | .13 | .20 |
Ever | 892 | 120 | Referent | 0.59 | 0.33 to 1.05 | 1.06 | 0.62 to 1.79 | 1.20 | 0.62 to 2.31 | .29 |
Abbreviations: LACE, Life After Cancer Epidemiology; HR, hazard ratio; MET, metabolic equivalent; BMI, body mass index.
Adjusted for age at diagnosis, total energy intake (kcal), race, BMI at enrollment, weight change from before diagnosis to baseline, smoking, menopausal status at diagnosis, stage of cancer, hormone receptor status, and treatment as designated in Tables 2 and 3.